Journal Reviews

American Journal of Rhinology & Allergy cover image.

Serum biomarkers for CRSwNP

5 January 2022 | | ENT, Maxillofacial Surgery, Rhinology / Sinus | Lund Mackay score, Pentraxin-3, Sinonasal Outcome Test 22, biomarkers, chronic rhinosinusitis with nasal polyposis, immunoglobulin E, interleukin-17, polyposis recurrence, sinusitis

This cross-sectional comparative study looked at 50 patients with nasal polyps who, at the time of diagnosis, also had a blood test evaluating serum total IgE, IL-17 and Pentraxin-3. The study assesses whether these blood markers are useful in the...

ALLERGY cover

CRSwNP, another monoclonal antibody

1 July 2019 | | Rhinology / Sinus | biomarkers, dupilumab, nasal polyposis, nasal secretions, type 2 inflammation

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...