Journal Reviews

American Journal of Rhinology & Allergy cover image.

Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody

1 July 2021 | | ENTA-Rhinology / Sinus | MLK, SNOT-22, allergic fungal rhinosinusitis, anti-IL-5, asthma, eosinophils, mepolizuma, nucala, prednisone rescue, recalcitrant

Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...