Journal Reviews

Role of oral and intranasal steroids in the management of otitis media with effusion

1 May 2018 | | Otitis Media With Effusion, Steroids, Audiometry, Tympanometry

Inflammation is considered an important factor in the pathogenesis and continuation of otitis media with effusion. Theoretically, this may support the use of steroids, oral or intranasal in the management of this condition. This study comprised three well matched groups...

A review of topical treatments for chronic rhinosinusitis

1 November 2017 | | Chronic rhinosinusitis, Nebulizers, Sinus irrigations, Steroids, Topical

Topical nasal treatment is considered the mainstay treatment for chronic rhinosinusitis (CRS). The authors reviewed the effectiveness of saline irrigation, topical corticosteroids, topical antibiotics and topical antifungals in the treatment of CRS. Large volume saline irrigation was found to be...

Role of intranasal steroids after radiotherapy for nasopharyngeal carcinoma

1 March 2017 | | Nasopharyngeal Carcinoma, Radiotherapy, Sinusitis, Steroids

Rhinosinusitis often follows radiotherapy in the treatment of carcinoma of the nasopharynx. The interval and severity may vary with the dose of radiation and stage of the carcinoma. In this randomised, controlled study, patients who developed rhinosinusitis after radiotherapy treatment...

Use of topical steroids and antibiotics, compared to systemic antibiotics in the treatment of acute rhinusinusitis

1 January 2017 | | Absorption, Administration, Anti-Bacterial Agents, Bacterial Infections, Intranasal, Physiological, Randomized Controlled Trial, Rhinitis, Sinusitis, Steroids

Acute rhinusinusitis is mainly initiated by viral infections. Bacterial infection is usually superadded. The inflammatory cascade upregulates the pro-inflammatory mediators resulting in pain, nasal obstruction and nasal discharge. Local application of steroids and antibiotics could provide a higher concentration of...