Journal Reviews

Use of topical steroids and antibiotics, compared to systemic antibiotics in the treatment of acute rhinusinusitis

1 January 2017 | | Absorption, Administration, Anti-Bacterial Agents, Bacterial Infections, Intranasal, Physiological, Randomized Controlled Trial, Rhinitis, Sinusitis, Steroids

Acute rhinusinusitis is mainly initiated by viral infections. Bacterial infection is usually superadded. The inflammatory cascade upregulates the pro-inflammatory mediators resulting in pain, nasal obstruction and nasal discharge. Local application of steroids and antibiotics could provide a higher concentration of...