Journal Reviews

Method of delivery: all topical nasal corticosteroids are not made equal

1 July 2018 | | chronic rhinosinusitis, corticosteroid, intranasal spray, nasal polyps, irrigations, paranasal sinuses

There is an increasing body of evidence that the role of surgery for chronic rhinosinusitis is to facilitate the delivery of topical medical treatment – most notably, topical corticosteroids. Two recent studies, one using flow dynamics and another one examining...

IL-25 and nasal polyps, another target

1 May 2018 | | Th2 response, Chronic rhinosinusitis, interleukin 25, nasal polyp

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Stem cells in nasal polyposis

1 May 2018 | | CRSwNP, chronic rhinosinusitis, nasal polyps, stem cells, tissue regeneration

Chronic rhinosinusitis with nasal polyps (CRSwNP) is common and is multifactorial with increased T-helper 2 response and active role of interleukin 5. It can be associated with asthma and control of CRSwNP improves lower airway disease. Due to constant cellular...

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