Spotlight on Innovation

Graphic image showing how gene therapy works.

Hyposalivation: a review of current and future treatments

8 January 2024 | Sachin Tushar Patel, Ehsan Nawaz, Syed Irtiza Ali Shah, Zohaib Siddiqui, Keli Dusu | ENTA-ENT, ENTA-Head & Neck

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...

What is Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE)?

1 May 2018 | Reza Nouraei, James Richard Shorthouse, James Keegan, Fran Haigh, Kate Heathcote, Anil Patel, Michael Girgis | ENTA-ENT, ENTA-Head & Neck, ENTA-Laryngology / Swallowing / Voice

THRIVE is a physiological mechanism for oxygenating and ventilating patients who are under general anaesthesia and who have diminished or absent respiratory effort [1]. Classical ventilation requires bulk flow of gases into and out of the lungs driven by chest...

The use of THRIVE in laryngology and phonosurgery

1 May 2018 | Nicholas Gibbins, Anil Patel, Andrew McKechnie, Michael Peter Jennings | ENTA-ENT, ENTA-Head & Neck, ENTA-Laryngology / Swallowing / Voice

The team in Lewisham has been using THRIVE for our phonosurgical cases for about a year. Here, we discuss the pros, cons and potential pitfalls of setting up and using THRIVE as ventilation during anaesthesia rather than using an ML...