Hassan Mohammed

ENT SpR

North East Deanery, Newcastle, UK.

Latest Contribution

Zinc and rhinosinusitis

1 January 2019 |

Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...

Chronic rhinosinusitis, are we treating the same disease?

31 October 2018 | | Rhinology / Sinus | chronic rhinosinusitis, cluster analysis, difficult-to-treatment, nasal polyps

Chronic rhinosinusitis (CRS) is a heterogenic disease. The effects of heterogeneity on treatment outcome are not very clear. Authors used clinical features such as endoscopic findings scores and full blood count findings in addition to analysis of 35 molecular markers....

Interleukins, cilia and polyps

1 October 2018 | | Rhinology / Sinus | ERK1/2, IL-13, IL-13Rα2, MUC5AC, nasal mucosal inflammation

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...